Samoa Digital Library

Autonomic Brain Centers and Pathophysiology of COVID-19

Show simple item record

dc.contributor.author Chigr, Fatiha
dc.contributor.author Merzouki, Mohamed
dc.contributor.author Najimi, Mohamed
dc.date.accessioned 2020-11-26T02:56:41Z
dc.date.available 2020-11-26T02:56:41Z
dc.date.issued 2020-05
dc.identifier.citation ACS Chem. Neurosci. 2020, 11, 1520−1522 en_US
dc.identifier.uri ${sadil.baseUrl}/handle/123456789/139
dc.description 3 p. en_US
dc.description.abstract Accumulating data have now shown strong evidence that COVID-19 infection leads to the occurrence of neurological signs with different injury severity. Anosmia and agueusia are now well documented and included in the criteria list for diagnosis, and specialists have stressed that doctors screen COVID-19 patients for these two signs. The eventual brainstem dysregulation, due to the invasion of SARS CoV-2, as a cause of respiratory problems linked to COVID-19, has also been extensively discussed. All these findings lead to an implication of the central nervous system in the pathophysiology of COVID-19. Here we provide additional elements that could explain other described signs like appetite loss, vomiting, and nausea. For this, we investigated the role of brainstem structures located in the medulla oblongata involved in food intake and vomiting control. We also discussed the possible pathways the virus uses to reach the brainstem, i.e., neurotropic and hematogenous (with its two variants) routes. en_US
dc.language.iso en en_US
dc.publisher ACS Chemical Neuroscience en_US
dc.subject Coronavirus en_US
dc.subject COVID-19 en_US
dc.subject central nervous system en_US
dc.subject food intake control en_US
dc.subject nausea and vomiting en_US
dc.title Autonomic Brain Centers and Pathophysiology of COVID-19 en_US
dc.type Article en_US


Files in this item

This item appears in the following Collection(s)

Show simple item record

Search DSpace


Browse

My Account